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3,5-Diiodothyropropionic acid

CAS No. 1158-10-7

3,5-Diiodothyropropionic acid ( C082182; Ditpa cpd )

Catalog No. M26536 CAS No. 1158-10-7

3,5-Diiodothyropropionic acid is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3,5-Diiodothyropropionic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    3,5-Diiodothyropropionic acid is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).
  • Description
    3,5-Diiodothyropropionic acid is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).
  • Synonyms
    C082182; Ditpa cpd
  • Pathway
    Endocrinology/Hormones
  • Target
    THR
  • Recptor
    ABCB1; ABCG2; Met
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1158-10-7
  • Formula Weight
    510.1
  • Molecular Formula
    C15H12I2O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu ZX, et al. Tepotinib hydrochloride for the treatment of non-small cell lung cancer. Drugs Today (Barc). 2021 Apr;57(4):265-275.
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